RU-58841

What is RU-58841? RU-58841 (also known as PSK-3841 / HMR-3841) is a nonsteroidal androgen-receptor (AR) antagonist frequently used in laboratory studies of AR signaling and androgen-responsive skin/hair models. It was explored clinically in the 1990s–2000s as a topically active antiandrogen, but no FDA-approved product resulted and development was not continued after Phase II evaluations. Wikipedia Inxight Drugs Selected literature context Topical RU-58841 has been studied in preclinical models, including human scalp grafts on nude mice and primate models, as an AR-targeted compound in androgen-dependent skin biology. PubMed SpringerLink Specifications Synonyms: RU-58841; PSK-3841; HMR-3841 Wikipedia IUPAC/Preferred name (PubChem): 4-(3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile PubChem CAS: 154992-24-2…