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RU-58841
$60.00
What is RU-58841? RU-58841 (also known as PSK-3841 / HMR-3841) is a nonsteroidal androgen-receptor (AR) antagonist frequently used in laboratory studies of AR signaling and androgen-responsive skin/hair models. It was explored clinically in the 1990s–2000s as a topically active antiandrogen, but no FDA-approved product resulted and development was not continued after Phase II evaluations. Wikipedia Inxight Drugs Selected literature context Topical RU-58841 has been studied in preclinical models, including human scalp grafts on nude mice and primate models, as an AR-targeted compound in androgen-dependent skin biology. PubMed SpringerLink Specifications Synonyms: RU-58841; PSK-3841; HMR-3841 Wikipedia IUPAC/Preferred name (PubChem): 4-(3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile PubChem CAS: 154992-24-2…
Description
| Chemical Formula | C17H18F3N3O3 |
| Molecular Mass | ~369.34 Da |
| CAS Number | 154992-24-2 |
| Form | Solid small-molecule research compound |
| Shelf Life | 24 months (under recommended storage conditions) |
| Intended Use | For preclinical and in vitro research only |
| Storage | Store at −20 °C in a dry, light-protected environment |
In experimental research settings, RU-58841 is utilized as a non-steroidal androgen receptor antagonist to investigate androgen-dependent signaling pathways and receptor–ligand interactions under controlled laboratory conditions. Its small-molecule structure supports studies focused on receptor binding behavior, competitive inhibition dynamics, and transcriptional regulation mechanisms.
Preclinical investigations commonly employ RU-58841 in cell-based and biochemical assays to examine androgen receptor signaling modulation, pathway selectivity, and comparative activity versus other research antiandrogen compounds. Experimental outcomes may vary depending on model system, exposure duration, and assay design.
Intended for laboratory research use only. Not for human or animal consumption, medical diagnosis, cosmetic use, or therapeutic application.
Additional information
| Volume | 50MG/ML |
|---|
Description
| Chemical Formula | C17H18F3N3O3 |
| Molecular Mass | ~369.34 Da |
| CAS Number | 154992-24-2 |
| Form | Solid small-molecule research compound |
| Shelf Life | 24 months (under recommended storage conditions) |
| Intended Use | For preclinical and in vitro research only |
| Storage | Store at −20 °C in a dry, light-protected environment |
In experimental research settings, RU-58841 is utilized as a non-steroidal androgen receptor antagonist to investigate androgen-dependent signaling pathways and receptor–ligand interactions under controlled laboratory conditions. Its small-molecule structure supports studies focused on receptor binding behavior, competitive inhibition dynamics, and transcriptional regulation mechanisms.
Preclinical investigations commonly employ RU-58841 in cell-based and biochemical assays to examine androgen receptor signaling modulation, pathway selectivity, and comparative activity versus other research antiandrogen compounds. Experimental outcomes may vary depending on model system, exposure duration, and assay design.
Intended for laboratory research use only. Not for human or animal consumption, medical diagnosis, cosmetic use, or therapeutic application.
Additional information
| Volume | 50MG/ML |
|---|
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